Here are some other things to watch:
WILL HE TALK TO HER?: Panthers quarterback Cam Newton lost an endorsement deal on Thursday because the company perceived his comments to be "sexist" to a female reporter. Newton might face questions from at least one woman on Sunday because Fox assigned Pam Oliver to be the game's sideline reporter.
USUALLY Cleveland Cavaliers Jerseys PIVOTAL: Carolina has given up the ball five more times than it has forced turnovers, ranking ahead of only Chicago in the NFL in that key statistic. Newton has thrown five interceptions, three in a 21-point loss to New Orleans, to account for most of the Panthers' seven turnovers. Carolina's defense is Arizona Cardinals Jerseys No. 4 in yards allowed, but has forced just two turnovers to rank ahead of only Miami. The Lions, meanwhile, lead the league in forcing nine more turnovers than they have given up.
YOU AGAIN?: The Lions have seen plenty of Julius Peppers over the years, most recently in Green Bay and Chicago. Now, he's back in Carolina and the 37-year-old defensive end doesn't seem to be slowing down. He had his second two-sack game of the season in New England.
"I can't get away from that guy," Lions quarterback Matthew Stafford said. "He looks like the Julius Peppers I've played against my entire career."
BYRD ON A WIRE: Carolina lost starting safety Kurt Coleman for a month to a knee injury against the Patriots. They signed three-time Pro Bowl safety Jairus Byrd to Boston Bruins Jerseys add depth, giving them another experienced player in the secondary to go along with 36-year-old safety Mike Adams. It's unclear if Byrd will be ready to Los Angeles Dodgers Jerseys start or if the Panthers will stick with rookie Demetrious Cox, who replaced Coleman during last week's game.
The Panthers might not have to face rookie receiver Kenny Golladay, who was held out of practice Wednesday and Thursday with a hamstring injury and could miss a second straight game. Golladay scored two touchdowns in his NFL debut.
GROUND GAINS: Detroit is slowly improving its running game, going from among the NFL's worst to relatively average. Ameer Abdullah had a career-high 94 yards on 20 carries in last week's win over the Vikings and seemed to survive an injury scare. He went out late in the game with an ankle injury, but was cleared for a full practice on Thursday.
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